Internet of Things (IoT) platform that provides Real World Data (RWD) & Real-World Evidence (RWE) for CTs. The platform is composed of a) the participants’ smartphone and other devices; b) the participants’ smartphone app to answer surveys and collect passive data; c) a website that is used to set-up the study’s settings: researcher management, participant recruitment, device set-up, app settings to define which data is collected from the users’ smartphones; and, the customizable written or voice surveys that each participant needs to answer; and, d) a server that collects the data from devices and applies proprietary AI algorithms to remotely monitor the symptoms of a participant (heart rate, time spent at home, sleep, etc.).